The advancement of technology in life science has created a need for improved accuracy and precision in pipetting small volumes1 from 50 nL up to and above 10 μL. Tomtec has adapted ink-jet technology to meet this need in their Nano pipettor heads. A coefficient of variation (CV) of 5% is achievable at 50-nL volumes, improving to 1–2% at 1 μL and above. A pipettor must aspirate from a source and dispense to a destination, then repeat the process without detectable carryover. The Nano head 8 and Nano head 16 achieve this utilizing a novel standpipe design that permits a fast wash through of the liquid handling channels. Each pipettor may be individually controlled, creating another dimension in pipetting flexibility.