Efficient Sample Logistics: From the Chemist to the Assay Plate and Beyond

Received 22 November 2005

A seamless workflow from the medicinal chemist to the screening collections and then to project team assays for new chemical entities has been achieved, by using 1.4-ml 2D bar-coded tubes, an automated tube store system, and a database built in-house. A process of sample collecting, logging, shipping, and sample reformatting has been established with a ComPOUND/ComMOTION automated tube store system at the heart of the process.

Keywords: Compound management, ComPOUND, 2D bar-coded tubes, compound database, automated compound store

Merck Sharp & Dohme, Essex, UK

Correspondence: Kevin W. Moore, Molecular & Cellular Neuroscience Department, Merck Sharp & Dohme, Terlings Park, Harlow, Essex CM20 2QR, UK. Phone: +44.1279.440400; Fax: +44.1279.440543

PII: S1535-5535(06)00003-7

doi:10.1016/j.jala.2006.01.002

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